What functions does the axon terminal perform in the nervous system?
The axon terminal is responsible for transmitting signals from a neuron to adjacent cells or neurons via chemical synapses. It releases neurotransmitters stored in synaptic vesicles into the synaptic cleft, facilitating communication across the synapse and influencing neuronal activity.
What happens when axon terminals are damaged?
When axon terminals are damaged, it can disrupt the transmission of nerve signals, impairing communication between neurons. This can result in loss of function or sensation, muscle weakness, or neurological disorders, depending on the affected neural circuits. Repair is often limited, although some regeneration may occur with proper medical intervention and rehabilitation.
How do axon terminals communicate with other neurons?
Axon terminals communicate with other neurons through synapses, where they release neurotransmitters into the synaptic cleft. These chemicals then bind to receptors on the postsynaptic neuron, triggering an electrical signal and facilitating neuronal communication.
How do axon terminals contribute to synaptic plasticity?
Axon terminals contribute to synaptic plasticity by releasing neurotransmitters that strengthen or weaken synaptic connections based on activity levels. Changes in neurotransmitter release, receptor sensitivity, and synaptic structure at the terminals facilitate learning, memory, and adaptive neural circuit modifications. This dynamic process underlies Hebbian plasticity, such as long-term potentiation or depression.
How are neurotransmitters released from the axon terminal?
Neurotransmitters are released from the axon terminal through a process called exocytosis. When an action potential reaches the terminal, it triggers the opening of voltage-gated calcium channels. Calcium ions enter the terminal, facilitating the fusion of synaptic vesicles with the presynaptic membrane and releasing neurotransmitters into the synaptic cleft.