What is the role of prolactin in the human body?
Prolactin primarily stimulates breast development and milk production in women after childbirth. It also influences immune system regulation, reproductive health, and mood regulation. In men, prolactin plays a minor role in reproductive health and the maintenance of general well-being.
How does prolactin affect fertility?
Prolactin affects fertility by influencing reproductive hormone levels. Elevated prolactin can inhibit the secretion of gonadotropin-releasing hormone (GnRH), reducing levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which can lead to disrupted ovulation in women and decreased testosterone production in men, impairing fertility.
What causes high prolactin levels?
High prolactin levels, or hyperprolactinemia, can be caused by a prolactinoma (a benign pituitary tumor), medications (such as antipsychotics and antiemetics), hypothyroidism, kidney disease, liver disease, stress, and chest wall injury. Pregnancy and breastfeeding also naturally elevate prolactin levels.
Can stress influence prolactin levels?
Yes, stress can influence prolactin levels. Physical or emotional stress can lead to increased secretion of prolactin from the pituitary gland. Stress-induced hyperprolactinemia is a documented phenomenon, as stress activates the hypothalamic-pituitary-adrenal axis, which can affect prolactin release.
How do prolactin levels impact breastfeeding?
Prolactin plays a crucial role in breastfeeding by stimulating milk production in the mammary glands after childbirth. Higher levels of prolactin are associated with increased milk supply, enabling effective nursing. It is regulated by sucking stimulus, which ensures consistent prolactin secretion to maintain lactation.