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Physiology of Stress

Your heart is racing in your chest, and your breathing is getting quicker and quicker. Do these symptoms sound familiar? These are some physiological symptoms of stress. What else happens to our bodies when we are stressed?

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Physiology of Stress

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Your heart is racing in your chest, and your breathing is getting quicker and quicker. Do these symptoms sound familiar? These are some physiological symptoms of stress. What else happens to our bodies when we are stressed?

  • What is the physiological model of stress definition?
  • Are there physiological symptoms of stress?
  • What are the physiological effects of stress?
  • What is the physiological impact of stress?
  • And are there physiological causes of stress?

Physiology of Stress stressed woman at her desk StudySmarterFig. 1 - Stressed woman at her desk.

The Physiological Model of Stress: Definition

We often think of stress as something that weighs on us mentally. When we are stressed, our minds are preoccupied with the situation or circumstances causing us stress. These stressors might make us anxious or even depressed. This is grouped as a psychological stress model because it involves how we cognitively react to stress.

However, we experience and process stress in different ways. We know how we psychologically process stress, but what about the physiological model of stress?

The physiological model of stress refers to how our physical body processes, reacts to and is changed by stress.

Stressful events might affect us psychologically and leave us more prone to depression or anxiety or cause our general optimism to take a hit. Below, let's explore the physiology of stress.

The Physiological Symptoms of Stress

Stress can show up comprehensively across the body, affecting virtually all the body's systems. You might notice shortness of breath or a racing pulse when you become stressed. This is stress acting upon your cardiovascular system.

Stress also affects the gastrointestinal system by causing symptoms such as heartburn or indigestion.

Stress can deregulate our nervous system, affect our sleep cycle, and cause us to feel fatigued or lose or gain weight. Chronic stress has even been known to affect the menstrual cycle and women's ability to conceive.

The Physiological Effects of Stress

Another example of the body's response to stress is altered PH levels. The physiology of stress is when the homeostatic condition of the body changes as a result of encountering stressors. Researchers have identified several parts of the body that are activated when stressed, which are responsible for the physiological changes that occur.

Homeostasis is the optimal condition that the body needs to be in, to work effectively.

The stress response is considered innate in animals (including humans). If the body is exposed to stress for too long, then the physiological effects of stress can cause long-term damage.

However, stressful encounters have short-term evolutionary advantages, such as helping us perceive and react to potentially harmful stimuli and situations. Therefore, it is essentially a survival mechanism.

When stressed, many changes occur in the body; the General Adaptation Syndrome (GAS) describes the stages of stress that we experience and how these affect the physiology of our body.

Physiology of Stress: The General Adaptation Syndrome (GAS)

The GAS model was proposed by Selye (1936) to describe what happens to the body when we experience stressors and how the body adapts to stressful situations.

Stressors are negative stimuli, events or threats that cause a physiological ‘stress’ response in the body. Some stressors are divorce, moving house, injury, job loss, deadlines, and work.

The model states that there are three stages that we experience when we encounter a stressor.

GAS Stages
Description
Stage 1: Alarm The body kicks into 'fight-or-flight mode' after encountering a stressor; this leads to a physiological response such as increased heart rate and quickened breathing.
Stage 2: ResistanceThe parasympathetic branch is activated to try and calm the body and counteract the symptoms triggered by the alarm phase. The body does this by releasing the hormones adrenaline and cortisol. During this stage, a lot of the body’s energy is depleted.
Stage 3: ExhaustionThe body has used up all its energy resources and can’t counteract stress symptoms. Continual exposure to this stage leads to cardiovascular and immunity problems.

Physiology of Stress doctor and patient in emergency room StudySmarterFig. 2 - Doctor and patient in the emergency room.

The Physiological Impact of Stress

Prolonged stress can leave a lasting impact on the body. It can affect our cardiovascular system and the hormones in our body.

The hormones that are released when we are stressed are adrenaline and cortisol. These hormones are released to stop the adverse effects of stress damaging our bodies.

Adrenaline is released when we are stressed; this hormone affects the sympathetic nervous system and triggers the fight-and-flight response. An increase in adrenaline leads to an increased heart rate, which prepares the by for either:

  1. Fight: an increase in energy leads to heightened awareness of your senses so that you are best equipped to fight.
  2. Or Flight: an increase in energy so that you can run away.

Too much and frequent exposure to high adrenaline levels causes the heart to work harder, leading to cardiovascular problems.

Cortisol is a hormone that helps regulate blood sugar levels, metabolism and inflammation. Cortisol is also released when we encounter stressors. The hormone ‘turns off’ systems that are not needed in the body. The body is then better prepared to deal with stressors and can stop cells and hormones involved in inflammatory responses from being released.

The body needs to have a balanced amount of cortisol to function correctly.

If we experience high cortisol levels too frequently, it can lead to health issues, such as immunosuppression. Chronic stress causes cells to become resistant to cortisol. Cortisol becomes less effective at stopping cells/hormones from causing inflammatory responses, compromising the functioning of the immune system.

Too little cortisol can cause tiredness, muscle weakness, weight loss and low blood pressure.

Physiological Causes of Stress

Two different pathways are activated when we experience stressful situations: the Hypothalamic Pituitary Adrenal (HPA) system and the Sympathomedullary Pathway (SAM).

The purpose of the HPA system is to try and maintain homeostasis when we experience stress. The body needs to stay in optimal conditions (like a specific temperature or pH to work properly); this is homeostasis.

When we encounter stressful situations, the hypothalamus is activated, which activates the pituitary gland. The pituitary gland releases a hormone, ACTH (adrenocorticotropic hormone), which is transported to the adrenal glands, the structure responsible for the production of cortisol.

Corticosteroids are produced in the adrenal cortex and are also a synthetic version of cortisol, mimicking the effects of cortisol in the body.

Cortisol turns off the systems, such as inflammatory reactions caused by the activation of the SAM pathway.

People with high blood pressure are more likely to get inflammatory diseases.

During stressful situations, the hypothalamus also activates the adrenal medulla, which is part of the Autonomic Nervous System. The adrenal medulla causes the release of adrenaline that is responsible for the 'fight-or-flight' mode that we enter when we are stressed.

The activation of this region leads to increased activity in the sympathetic nervous system and decreased activity in the parasympathetic nervous system; this is known as the SAM pathway.

Adrenaline (a hormone made in the adrenal medulla) and noradrenaline (a neurotransmitter made in the sympathetic nervous system) can act as hormones and neurotransmitters. Both help the body prepare for fight-or-flight.

Physiology of Stress - Key takeaways

  • The physiology of stress is when the homeostatic condition of the body changes as a result of encountering a stressor.
  • Homeostasis is the optimal condition that the body needs to be in, to work effectively.
  • The hormones that are released when we are stressed are adrenaline and cortisol.
  • The GAS model was proposed by Selye (1936) to describe what happens to the body when we experience stressors.
  • Two different pathways are activated when we experience stressful situations: the Hypothalamic Pituitary Adrenal (HPA) system and the Sympathomedullary Pathway (SAM).

Frequently Asked Questions about Physiology of Stress

When you experience stressful situations, you may notice an increase in your heart and breathing rate; this is the physiological symptom of stress.

Heart rate and breathing rate increase, or the body's Ph levels also change. 

When we are exposed to physiological symptoms of stress for too long, then it can cause inflammation. Inflammation has been linked to many mental health illnesses. 

This is also known as the General Adaptation Syndrome (GAS) model, which explains the three stages of stress (the alarm phase, the phase of adaptation and the phase of exhaustion) and the effects these have on the body. 

These have been linked to inflammation and cardiovascular problems. 

Test your knowledge with multiple choice flashcards

What did Horwatt et al. (1988) show acute stress responses? Pick one.

Which researchers demonstrated the effects of chronic stress on the immune system?

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